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Whereas the two toxins displayed identical cytotoxic potencies, TcdBNAP1 induced a stronger proinflammatory response than TcdBNAP1V as determined in ex vivo experiments and animal models. LC-MS analysis of glycopeptides of recombinant monoclonal antibodies by a rapid digestion procedure. Hrs recruits ROCK1 to the membrane, which is required for the activation of NHE1 and an increase in submembranous intracellular pH occurring during macropinocytosis. Mouse strain marley drug sildenafil differences in metabolic fluxes and function of ex vivo working hearts.

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